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Results: The inner commonplace and amoxicillin penicillin eluted about 4.2 and 5.2 min, respectively at a stream fee of 1.3 ml/min. The imply absolute restoration of AMO in plasma was 90.0% at 3 mug/ml, 98.6% at 25 mug/ml and 95.Three at 50 mug/ml. The assay showed wonderful relationships between peak peak ratios. Plasma concentrations (r(2) greater than or equal to 0.999).999). The restrict of quantification was 1 mug/ml, based on 200 l of plasma. The geometric mean of Amoxicihna/Amoxi(R) 500 mg capsules individual share ratio was 101.4% for Amoxicilina 500 mg AUC(0-8h), and 99.9% for C-max. The 90% confidence intervals were 98.3-104.4% and 95.7-103.9%, respectively. Conclusion: This straightforward, fast and selective methodology is amoxicillin appropriate for pharmacokinetic, bioavailability and bioequivalence studies. Since the 90% Cl for each C-max and AUC(0-8h) lies within the 80-125% interval proposed by the Food and Drug Administration, it was concluded that Amoxicilina 500 mg capsules was bioequivalent to Amoxil(R) capsules 500 mg, when it comes to both the rate and extent of absorption. amoxicilina 500 mg